ITERATIVE NON-SEQUENTIAL PROTEIN STRUCTURAL ALIGNMENT
نویسندگان
چکیده
منابع مشابه
Iterative Non-Sequential protein Structural Alignment
Structural similarity between proteins gives us insights into their evolutionary relationships when there is low sequence similarity. In this paper, we present a novel approach called SNAP for non-sequential pair-wise structural alignment. Starting from an initial alignment, our approach iterates over a two-step process consisting of a superposition step and an alignment step, until convergence...
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The study of non-sequential alignments, with different connectivity of the aligned fragments in the proteins being compared can offer a more complete picture of the structural, evolutionary and functional relationship between two proteins, than what is possible purely with sequential alignments. The design of techniques for non-sequential protein structure alignment therefore, constitutes an im...
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A fundamental issue in studies of protein structure and function is how to identify the conserved common core in multiple protein structures. The existing algorithms work well for proteins family such as those in HOMSTRAD but are not satisfactory for general multiple structure alignment problems, especially in some challenging cases, such as the occurrence of circular permutations. In this pape...
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ژورنال
عنوان ژورنال: Journal of Bioinformatics and Computational Biology
سال: 2009
ISSN: 0219-7200,1757-6334
DOI: 10.1142/s0219720009004205